Welkom bij THIM Hogeschool voor Fysiotherapie & Bohn Stafleu van Loghum
THIM Hogeschool voor Fysiotherapie heeft ervoor gezorgd dat je Mijn BSL eenvoudig en snel kunt raadplegen. Je kunt je links eenvoudig registreren. Met deze gegevens kun je thuis, of waar ook ter wereld toegang krijgen tot Mijn BSL. Heb je een vraag, neem dan contact op met helpdesk@thim.nl.
Om ook buiten de locaties van THIM, thuis bijvoorbeeld, van Mijn BSL gebruik te kunnen maken, moet je jezelf eenmalig registreren. Dit kan alleen vanaf een computer op een van de locaties van THIM.
Eenmaal geregistreerd kun je thuis of waar ook ter wereld onbeperkt toegang krijgen tot Mijn BSL.
Login
Als u al geregistreerd bent, hoeft u alleen maar in te loggen om onbeperkt toegang te krijgen tot Mijn BSL.
A 64-year-old man suffering from an acute posterior wall myocardial infarction underwent primary percutaneous coronary intervention. After several aspiration attempts, tirofiban infusion and pre- and post-dilatation, a bare-metal stent was successfully implanted in the culprit right coronary artery. While the patient did not show any neurological symptoms before or during the procedure, he exhibited hemiplegia and loss of spontaneous speech. Additional magnetic resonance imaging showed an extensive brain stem infarction. This is the first report of a brain stem infarction as a complication of percutaneous coronary intervention.
The online version of this article (doi:10.1007/s12471-015-0717-2) contains supplementary material, which is available to authorized users.
Here we present a case of a 64-year-old man, without any history of cardiovascular risk factors or other comorbidities, who underwent acute percutaneous coronary intervention (PCI) for an acute posterior wall myocardial infarction. Coronary angiography revealed an occluded right coronary artery (Fig. 1a, Online Video 1). In addition, the left circumflex coronary artery showed a non-occlusive thrombus, and the left anterior descending coronary artery revealed a Thrombolysis in Myocardial Infarction grade II flow (Fig. 1b, Online Video 2). After several aspiration attempts and intracoronary administration of tirofiban, the right coronary artery could be reopened with several pre-dilatations and implantation of a Driver Sprint bare-metal 4.5 15-mm stent (Medtronic Inc, Minnesota, USA) with subsequent 5.0 NC balloon post-dilatation. Because of the high thrombus load, successful reperfusion of the posterolateral branch was not possible (Fig. 1c, Online Video 3). A temporary pacemaker was placed before the PCI due to bradycardia. After the procedure, the patient became hemiplegic and exhibited loss of spontaneous speech. Cerebral magnetic resonance imaging revealed an extensive left-sided infarction in the brain stem expanding into the cerebral and cerebellar peduncle (Fig. 2). Thrombolysis was not possible, as dual anti-platelet therapy, heparinisation and continuous intravenous tirofiban had already been initiated. Subsequently, he was mechanically ventilated and treated with antibiotics for 6 days after which he developed aspiration pneumonia caused by neural dysphagia. Although he was extubated after 9 days, he received a tracheostoma due to persistent dysphagia and high risk for aspiration. He was transferred to the stroke unit for further rehabilitation. Coronary angiography and/or percutaneous coronary interventions have been associated with cerebral ischaemic complications. The complication rate varies between 0.07 and 0.4 % of the procedures [1‐4]. However, a brain stem infarction is highly unusual compared with cerebral stroke considering the difficult anatomical path for an embolus originating from the aortic arch. Before the embolus reaches the basilar artery, it needs to pass through the subclavian (or the brachiocephalic trunk for right-sided lesions) and the vertebral artery. To our knowledge, this is the first report of an acute pontine infarction as a complication of percutaneous coronary intervention.
Fig. 1
Coronary angiography of the a culprit lesion in the right coronary artery, b stenotic lesion in the left circumflex coronary artery and c right coronary artery after stent placement
×
Fig. 2
Transversal and sagittal views of the brain stem using T2-weighted magnetic resonance imaging. A left-sided brain stem infarction expands to the cerebral and cerebellar peduncle (arrows). A anterior, P posterior, R right, L left
×
Funding
None.
Conflict of interest
Dr. F. Arslan is an associate editor of the Netherlands Heart Journal.
Open Access This article is distributed under the terms of the Creative Commons Attribution License which permits any use, distribution, and reproduction in any medium, provided the original author(s) and the source are credited.
Het Netherlands Heart Journal wordt uitgegeven in samenwerking met de Nederlandse Vereniging voor Cardiologie. Het tijdschrift is Engelstalig en wordt gratis beschikbaa ...