In this chapter, we describe how to prepare for patients for laparoscopic operations. We provide an overview of what is important to check pre-operatively. Enhanced recovery is the new strategy; laparoscopy should facilitate enhanced recovery. Short-acting drugs in anesthesia are becoming more important. Medications that are used for anesthesia, analgesia, nausea, vomiting, and relaxation are explained. Abdominal pressure is increased when CO2 is insufflated, and the chapter explains how to manage the ventilation and what should be monitored in patients. Fluid balance is important, patients lose a lot of fluid during laparoscopy due to evaporation. The positioning of the patients should be checked before the surgery starts because the patient is fully covered with sterile drapes. In short, an overview is provided for the management of a laparoscopic surgery by an operating team.