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Journal of Autism and Developmental Disorders
Gepubliceerd in:

01-02-2009 | Original Paper

Autism symptoms in Attention-Deficit/Hyperactivity Disorder: A Familial trait which Correlates with Conduct, Oppositional Defiant, Language and Motor Disorders

Auteurs: Aisling Mulligan, Richard J. L. Anney, Myra O’Regan, Wai Chen, Louise Butler, Michael Fitzgerald, Jan Buitelaar, Hans-Christoph Steinhausen, Aribert Rothenberger, Ruud Minderaa, Judith Nijmeijer, Pieter J. Hoekstra, Robert D. Oades, Herbert Roeyers, Cathelijne Buschgens, Hanna Christiansen, Barbara Franke, Isabel Gabriels, Catharina Hartman, Jonna Kuntsi, Rafaela Marco, Sheera Meidad, Ueli Mueller, Lamprini Psychogiou, Nanda Rommelse, Margaret Thompson, Henrik Uebel, Tobias Banaschewski, Richard Ebstein, Jacques Eisenberg, Iris Manor, Ana Miranda, Fernando Mulas, Joseph Sergeant, Edmund Sonuga-Barke, Phil Asherson, Stephen V. Faraone, Michael Gill

Gepubliceerd in: Journal of Autism and Developmental Disorders | Uitgave 2/2009

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Abstract

It is hypothesised that autism symptoms are present in Attention-Deficit/Hyperactivity Disorder (ADHD), are familial and index subtypes of ADHD. Autism symptoms were compared in 821 ADHD probands, 1050 siblings and 149 controls. Shared familiality of autism symptoms and ADHD was calculated using DeFries-Fulker analysis. Autism symptoms were higher in probands than siblings or controls, and higher in male siblings than male controls. Autism symptoms were familial, partly shared with familiality of ADHD in males. Latent class analysis using SCQ-score yielded five classes; Class 1(31%) had few autism symptoms and low comorbidity; Classes 2–4 were intermediate; Class 5(7%) had high autism symptoms and comorbidity. Thus autism symptoms in ADHD represent a familial trait associated with increased neurodevelopmental and oppositional/conduct disorders.
volgende artikel Autism Symptoms in Attention-Deficit/Hyperactivity Disorder: A Familial Trait which Correlates with Conduct, Oppositional Defiant, Language and Motor Disorders
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Metagegevens
Titel
Autism symptoms in Attention-Deficit/Hyperactivity Disorder: A Familial trait which Correlates with Conduct, Oppositional Defiant, Language and Motor Disorders
Auteurs
Aisling Mulligan
Richard J. L. Anney
Myra O’Regan
Wai Chen
Louise Butler
Michael Fitzgerald
Jan Buitelaar
Hans-Christoph Steinhausen
Aribert Rothenberger
Ruud Minderaa
Judith Nijmeijer
Pieter J. Hoekstra
Robert D. Oades
Herbert Roeyers
Cathelijne Buschgens
Hanna Christiansen
Barbara Franke
Isabel Gabriels
Catharina Hartman
Jonna Kuntsi
Rafaela Marco
Sheera Meidad
Ueli Mueller
Lamprini Psychogiou
Nanda Rommelse
Margaret Thompson
Henrik Uebel
Tobias Banaschewski
Richard Ebstein
Jacques Eisenberg
Iris Manor
Ana Miranda
Fernando Mulas
Joseph Sergeant
Edmund Sonuga-Barke
Phil Asherson
Stephen V. Faraone
Michael Gill
Publicatiedatum
01-02-2009
Uitgeverij
Springer US
Gepubliceerd in
Journal of Autism and Developmental Disorders / Uitgave 2/2009
Print ISSN: 0162-3257
Elektronisch ISSN: 1573-3432
DOI
https://doi.org/10.1007/s10803-008-0621-3

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