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Netherlands Heart Journal
Gepubliceerd in:

01-08-2011 | Original Article

Failure of epicardial pacing leads in congenital heart disease: not uncommon and difficult to predict

Auteurs: M. C. Post, W. Budts, A. Van de Bruaene, R. Willems, B. Meyns, F. Rega, M. Gewillig

Gepubliceerd in: Netherlands Heart Journal | Uitgave 7-8/2011

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Abstract

Aims

We evaluate the incidence of epicardial lead failure and try to identify risk factors in patients with congenital heart disease.

Methods

All patients with a congenital heart defect and an epicardial pacing system, implanted within a timeframe of 25 years, were included in this study. Patients’ medical records and lead data were reviewed. Lead failure was defined as the primary endpoint.

Results

In total 198 active epicardial leads (atrial 40, ventricular 158) were implanted in 93 patients (median age at implantation 4.4 years (range 0–58.6)). During a total follow-up of 1235 lead-years, 29 lead failures (14.6%, 4 atrial, 25 ventricular) were documented in 22 patients (23.7%). Lead failure occurred at a median time period of 4.8 years (range 1.2–24.1) after implantation. Five-year freedom of lead failure was 88%. The only independent predictor for lead failure was the age at implantation (HR 0.44; 95%CI 0.20–0.97, p = 0.04), other characteristics failed to predict lead failure. Sudden cardiac death occurred in four patients (4.3%), in one a lead failure was documented.

Conclusion

A high incidence of epicardial lead failures is found in patients with congenital heart disease. Unfortunately, it is difficult to predict this potentially life-threatening complication.
vorige artikel GRACE and TIMI risk scores but not stress imaging predict long-term cardiovascular follow-up in patients with chest pain after a rule-out protocol
volgende artikel The role of multi-slice computed tomography in stable angina management: a current perspective
Literatuur
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Beaufort-Krol GC, Mulder H, Nagelkerke D, et al. Comparison of longevity, pacing, and sensing characteristics of steroid-eluting epicardial versus conventional endocardial pacing leads in children. J Thorac Cardiovasc Surg. 1999;117:523–8.PubMedCrossRef
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Metagegevens
Titel
Failure of epicardial pacing leads in congenital heart disease: not uncommon and difficult to predict
Auteurs
M. C. Post
W. Budts
A. Van de Bruaene
R. Willems
B. Meyns
F. Rega
M. Gewillig
Publicatiedatum
01-08-2011
Uitgeverij
Bohn Stafleu van Loghum
Gepubliceerd in
Netherlands Heart Journal / Uitgave 7-8/2011
Print ISSN: 1568-5888
Elektronisch ISSN: 1876-6250
DOI
https://doi.org/10.1007/s12471-011-0158-5

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