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01-04-2015 | Original Paper

Risk of Autism Associated With General Anesthesia During Cesarean Delivery: A Population-Based Birth-Cohort Analysis

Auteurs: Li-Nien Chien, Hsiu-Chen Lin, Yu-Hsuan Joni Shao, Shu-Ti Chiou, Hung-Yi Chiou

Gepubliceerd in: Journal of Autism and Developmental Disorders | Uitgave 4/2015

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Abstract

The rates of Cesarean delivery (C-section) have risen to >30 % in numerous countries. Increased risk of autism has been shown in neonates delivered by C-section. This study examined the incidence of autism in neonates delivered vaginally, by C-section with regional anesthesia (RA), and by C-section with general anesthesia (GA) to evaluate the risk of autism associated with C-section and obstetric anesthesia. During a mean follow-up of 4.3 years, the incidence of autism was higher in neonates delivered by C-section with GA than in neonates delivered vaginally, with an adjusted risk of 1.52 (95 % confidence interval 1.18–1.94). However, the adjusted risk of autism in neonates delivered by C-section with RA and in neonates delivered vaginally was nonsignificantly different.
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Metagegevens
Titel
Risk of Autism Associated With General Anesthesia During Cesarean Delivery: A Population-Based Birth-Cohort Analysis
Auteurs
Li-Nien Chien
Hsiu-Chen Lin
Yu-Hsuan Joni Shao
Shu-Ti Chiou
Hung-Yi Chiou
Publicatiedatum
01-04-2015
Uitgeverij
Springer US
Gepubliceerd in
Journal of Autism and Developmental Disorders / Uitgave 4/2015
Print ISSN: 0162-3257
Elektronisch ISSN: 1573-3432
DOI
https://doi.org/10.1007/s10803-014-2247-y