This study aims to characterize the relationships between intrinsic motivation toward physical activity, mindfulness, and physical activity level. We measured self-reported mindfulness, motivational regulation toward exercise, and physical activity level in 280 French students. Analyses conducted on 244 participants revealed that self-reported mindfulness moderates the relationship between intrinsic motivation toward exercise and physical activity levels. These findings may have implications for interventionists seeking to promote increased physical activity with mindfulness-based techniques. In fact, it seems that increasing mindfulness skills of individuals could improve their intrinsic motivation to exercise and, thus, physical activity.