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Journal of Psychopathology and Behavioral Assessment

Gepubliceerd in:

28-07-2021

Monoamine Oxidase-A and Conduct Problems in Children: The Role of Affective Decision-Making

Auteurs: Valentina Levantini, Cameron Powe, John E. Lochman, Andrea Glenn

Gepubliceerd in: Journal of Psychopathology and Behavioral Assessment | Uitgave 1/2022

Abstract

Genetic factors are a well-established risk factor for children's conduct problems. Specifically, the low activity variant of the Monoamine Oxidase-A (MAOA) gene is one of the most investigated. Most studies focused on MAOA's interaction with environmental factors, while little is known about the possible interaction with psychological processes, such as affective decision-making (ADM). The current study is aimed to investigate whether MAOA variants, ADM skills, and their interaction are associated with higher levels of teacher-reported conduct problems in a sample of at-risk children. DNA was extracted from a sample of 157 at-risk children (mean age 10.24 years, range 9.17–11.79, 70% boys). ADM skills were assessed with the Iowa Gambling Task. Children's conduct problems were measured with the Behavior Assessment System for Children-Teacher Rating Scales (BASC-TRS). Regression results showed that ADM skills significantly interacted with MAOA variants in predicting children's conduct problems. Among children with the low activity MAOA variant, conduct problems were significantly higher in children with lower ADM. Results suggest that ADM may be a protective factor for children with the low activity variant and shield them from the genetic variant's risks. Treatment implications are discussed.

vorige artikel Examining the Dimensionality of Anxiety and Depression: a Latent Profile Approach to Modeling Transdiagnostic Features

volgende artikel Interaction of Psychopathic Traits Dimensions in the Prediction of Psychological and Physical Child-to-Parent Violence in Adolescents

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Titel: Monoamine Oxidase-A and Conduct Problems in Children: The Role of Affective Decision-Making
Auteurs: Valentina Levantini
Cameron Powe
John E. Lochman
Andrea Glenn
Publicatiedatum: 28-07-2021
Uitgeverij: Springer US
Gepubliceerd in: Journal of Psychopathology and Behavioral Assessment / Uitgave 1/2022
Print ISSN: 0882-2689
Elektronisch ISSN: 1573-3505
DOI: https://doi.org/10.1007/s10862-021-09917-9

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Monoamine Oxidase-A and Conduct Problems in Children: The Role of Affective Decision-Making

Abstract

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