Skip to main content
Mijn bibliotheek
Shop
Nieuws Boeken Tijdschriften Toetsvragen Web-tv Video Audio
Tips voor Mijn BSL
Inloggen

Welkom bij THIM Hogeschool voor Fysiotherapie & Bohn Stafleu van Loghum

THIM Hogeschool voor Fysiotherapie heeft ervoor gezorgd dat je Mijn BSL eenvoudig en snel kunt raadplegen. Je kunt je links eenvoudig registreren. Met deze gegevens kun je thuis, of waar ook ter wereld toegang krijgen tot Mijn BSL. Heb je een vraag, neem dan contact op met helpdesk@thim.nl.

» Andere revante producten voor THIM studenten en medewerkers.

Registreer

Om ook buiten de locaties van THIM, thuis bijvoorbeeld, van Mijn BSL gebruik te kunnen maken, moet je jezelf eenmalig registreren. Dit kan alleen vanaf een computer op een van de locaties van THIM.

Eenmaal geregistreerd kun je thuis of waar ook ter wereld onbeperkt toegang krijgen tot Mijn BSL.

Login

Als u al geregistreerd bent, hoeft u alleen maar in te loggen om onbeperkt toegang te krijgen tot Mijn BSL.

Inloggen
Top
Quality of Life Research
Gepubliceerd in:

01-05-2007 | Brief Communication

Quality of life findings from a multicenter, multinational, observational study of patients with metastatic hormone-refractory prostate cancer

Auteurs: Patrick W. Sullivan, Parvez M. Mulani, Mayer Fishman, Darryl Sleep

Gepubliceerd in: Quality of Life Research | Uitgave 4/2007

Log in om toegang te krijgen
share
DELEN

Deel dit onderdeel of sectie (kopieer de link)

  • Optie A:
    Klik op de rechtermuisknop op de link en selecteer de optie “linkadres kopiëren”
  • Optie B:
    Deel de link per e-mail
    Link delen
publish
Publiceer nu

Abstract

Background

The assessment of health-related quality of life (HRQL) for patients with hormone-refractory prostate cancer (HRPC) is of paramount importance because new treatments have a modest impact on survival but side effects of treatment and disease symptoms can significantly impact HRQL.

Methods

This was an observational, non-interventional, multi-center, multi-national cohort study of patients with metastatic HRPC. Health-related quality of life was assessed using the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire (EORTC QLQ C30), the Functional Assessment of Cancer Therapy-Prostate (FACT-P) and the EQ-5D index. Mean changes from baseline to month 3, 6, and 9 were computed and tested using paired t-tests.

Results

FACT-P PCS, EQ-5D index and 10 of 14 EORTC domains were statistically significantly lower (P < 0.05) than the baseline scores at the 3, 6 and 9 month visits. The domains that did not reach statistical significance were cognitive functioning, insomnia, diarrhea and financial difficulties.

Conclusions

These data demonstrate that patients with metastatic HRPC experience rapid, significant deterioration in HRQL, highlighting the need for effective palliative therapy for men with HRPC.
vorige artikel Factors affecting health-related quality of life in women with recurrent breast cancer in Korea
volgende artikel Health-related quality of life in HIV-1-infected patients on HAART: a five-years longitudinal analysis accounting for dropout in the APROCO-COPILOTE cohort (ANRS CO-8)
Literatuur
1.
Petrylak, D. P., Tangen, C. M., & Hussain, M. H., et al. (2004). Docetaxel and estramustine compared with mitoxantrone and prednisone for advanced refractory prostate cancer. The New England Journal of Medicine, 351(15), 1513–520CrossRefPubMed
2.
Tannock, I. F., de Wit, R., & Berry, W. R., et al. (2004). Docetaxel plus prednisone or mitoxantrone plus prednisone for advanced prostate cancer. The New England Journal of Medicine, 351(15), 1502–512CrossRefPubMed
3.
Sommers, S. D., & Ramsey, S. D. (1999). A review of quality-of-life evaluations in prostate cancer. Pharmacoeconomics, 16(2), 127–40CrossRefPubMed
4.
Schellhammer, P., Cockett, A., & Boccon-Gibod, L. et al. (1997). Assessment of endpoints for clinical trials for localized prostate cancer. Urology, 49(4A Suppl), 27–8CrossRefPubMed
5.
McNaughton-Collins M, Walker-Corkery E, Barry MJ. Health-related quality of life, satisfaction, and economic outcome measures in studies of prostate cancer screening and treatment, 1990–000. (2004). Journal of the National Cancer Institute. Monographs. 33, 78–01
6.
Sandblom, G., Carlsson, P., Sennfalt, K., & Varenhorst, E. A. (2004). population-based study of pain and quality of life during the year before death in men with prostate cancer. British Journal of Cancer, 90(6), 1163–168CrossRefPubMed
7.
Litwin, M. S., Lubeck, D. P., Stoddard, M. L., Pasta, D. J., Flanders, S. C., & Henning, J. M. (2001). Quality of life before death for men with prostate cancer: Results from the CaPSURE database. Journal of Urology, 165(3), 871–75CrossRefPubMed
8.
Melmed, G. Y., Kwan, L., Reid, K., Litwin, M. S. (2002). Quality of life at the end of life: trends in patients with metastatic prostate cancer. Urology, 59(1), 103–09CrossRefPubMed
9.
Aaronson, N. K., Ahmedzai, S., & Bergman, B., et al. (1993). The European Organization for Research and Treatment of Cancer QLQ-C30: a quality-of-life instrument for use in international clinical trials in oncology. Journal of the Natonal Cancer Institute, 85(5), 365–76CrossRef
10.
Esper, P., Mo, F., Chodak, G., Sinner, M., Cella, D., & Pienta, K. J. (1997). Measuring quality of life in men with prostate cancer using the functional assessment of cancer therapy-prostate instrument. Urology, 50(6), 920–28CrossRefPubMed
11.
Saad, F., Gleason, D. M., & Murray, R., et al. (2002). A randomized, placebo-controlled trial of zoledronic acid in patients with hormone-refractory metastatic prostate carcinoma. Journal of the National Cancer Institute, 94(19), 1458–468PubMed
12.
Rodrigues, G., Bezjak, A., & Osoba, D., et al. (2004). The relationship of changes in EORTC QLQ-C30 scores to ratings on the Subjective Significance Questionnaire in men with localized prostate cancer. Quality of Life Research , 13(7), 1235–246CrossRefPubMed
13.
Osoba, D., Rodrigues, G., Myles, J., Zee, B., & Pater, J. (1998). Interpreting the significance of changes in health-related quality-of-life scores. Journal of Clinical Oncology, 16(1), 139–44PubMed
14.
King, M. T. (1996). The interpretation of scores from the EORTC quality of life questionnaire QLQ-C30. Quality of Life Research, 5(6), 555–67CrossRefPubMed
15.
Carducci, M. A., Nelson, J. B., Vogelzang, N. J., & Mulani, P. (2005). Determination of Clinically Meaningful Change (CMC) for FACT-P. (Paper presented at: 2005) Prostate Cancer Symposium.FL: Orlando
16.
Sullivan, P. W., Lawrence, W. F. Jr., & Ghushchyan, V. (2005). A National Catalogue of Preference-based Scores for Chronic Conditions in the U.S. Medical Care, 43(7), 736–49CrossRefPubMed
Metagegevens
Titel
Quality of life findings from a multicenter, multinational, observational study of patients with metastatic hormone-refractory prostate cancer
Auteurs
Patrick W. Sullivan
Parvez M. Mulani
Mayer Fishman
Darryl Sleep
Publicatiedatum
01-05-2007
Uitgeverij
Springer Netherlands
Gepubliceerd in
Quality of Life Research / Uitgave 4/2007
Print ISSN: 0962-9343
Elektronisch ISSN: 1573-2649
DOI
https://doi.org/10.1007/s11136-006-9156-2

Andere artikelen Uitgave 4/2007

Health-related quality of life in HIV-1-infected patients on HAART: a five-years longitudinal analysis accounting for dropout in the APROCO-COPILOTE cohort (ANRS CO-8)

  • Original Paper

What drives older women’s perceptions of health-related quality of life?

  • Original Paper

Documenting the rationale and psychometric characteristics of patient reported outcomes for labeling and promotional claims: the PRO Evidence Dossier

  • Review Paper

Item Response Theory Methods can Improve the Measurement of Physical Function by Combining the Modified Health Assessment Questionnaire and the SF-36 Physical Function Scale

  • Original Paper

The SF36 Version 2: critical analyses of population weights, scoring algorithms and population norms

  • Original Paper

Burden of restless legs syndrome on health-related quality of life

  • Original Paper