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Gepubliceerd in:

01-09-2008 | original article

Rescue of arterial function by angiotensin-(1-7): towards improvement of endothelial function by drug-eluting stents

Auteurs: B. E. Langeveld, R. H. Henning, B. J. G. L. de Smet, F. Zijlstra, A. Driessen, E. Tijsma, W. H. van Gilst, A. J. M. Roks

Gepubliceerd in: Netherlands Heart Journal | Uitgave 9/2008

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Extract

In-stent restenosis (ISR), the renarrowing of blood vessels after angioplasty with stent placement, is an ongoing clinical problem, affecting an increasing number of patients as the number of interventions increases. Recently, stents that elute cytostatic compounds have been shown to decrease restenosis, but the incidence of death or myocardial infarction after stenting has not improved, possibly due to a deficit in endothelial repair.1 Therefore, the search for less cytotoxic drugs that spare or protect the endothelium continues. In this perspective, drugs that intervene in the renin-angiotensin system are still eligible candidates.2
Literatuur
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Metagegevens
Titel
Rescue of arterial function by angiotensin-(1-7): towards improvement of endothelial function by drug-eluting stents
Auteurs
B. E. Langeveld
R. H. Henning
B. J. G. L. de Smet
F. Zijlstra
A. Driessen
E. Tijsma
W. H. van Gilst
A. J. M. Roks
Publicatiedatum
01-09-2008
Uitgeverij
Bohn Stafleu van Loghum
Gepubliceerd in
Netherlands Heart Journal / Uitgave 9/2008
Print ISSN: 1568-5888
Elektronisch ISSN: 1876-6250
DOI
https://doi.org/10.1007/BF03086167