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Journal of Autism and Developmental Disorders
Gepubliceerd in:

14-03-2020 | S.I. : Suicidality and Self-harm in Autism

Suicidality in Adults with Autism Spectrum Disorder: The Role of Depressive Symptomatology, Alexithymia, and Antidepressants

Auteurs: Andreia P. Costa, Cathia Loor, Georges Steffgen

Gepubliceerd in: Journal of Autism and Developmental Disorders | Uitgave 10/2020

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Abstract

People with autism spectrum disorder (ASD) have an increased risk of suicidality. However, the risk factors remain under-investigated. This study explored factors that increase suicidality risk in ASD. Through an online survey, 150 adults with ASD were compared to 189 control adults. Autistic traits, depressive symptomatology, alexithymia, and antidepressant intake were assessed on their contribution predicting suicidality. Among people with ASD, 63% scored above the cutoff for high suicidality risk. Increased autistic traits, depressive symptomatology, and antidepressant intake significantly predicted suicidality. Furthermore, among those with high levels of autistic traits, the risk of suicidality was increased if they also had high levels of alexithymia. These results highlight the importance of considering depression, antidepressants, and alexithymia to prevent suicidality in ASD.
vorige artikel Examining the Relationship Between Autism Traits and Sleep Duration as Predictors of Suicidality
volgende artikel Self-reported Suicidality in Male and Female Adults with Autism Spectrum Disorders: Rumination and Self-esteem
Literatuur
American Psychiatric Association. (2013). Diagnostic and statistical manual of mental disorders (5th ed.). Washington, DC: Author.
Angst, J., Angst, F., & Stassen, H. H. (1999). Suicide risk in patients with major depressive disorder. The Journal of Clinical Psychiatry, 60(2), 57–62.PubMed
Bagby, R. M., Taylor, G. J., & Parker, J. D. (1994). The twenty-item Toronto alexithymia scale—II. Convergent, discriminant, and concurrent validity. Journal of Psychosomatic Research, 38(1), 33–40.PubMedCrossRef
Balfe, M., & Tantam, D. (2010). A descriptive social and health profile of a community sample of adults and adolescents with Asperger syndrome. BMC Research Notes, 3(1), 300.PubMedPubMedCentralCrossRef
Baron-Cohen, S., Wheelwright, S., Skinner, R., Martin, J., & Clubley, E. (2001). The autism-spectrum quotient (AQ): Evidence from asperger syndrome/high-functioning autism, malesand females, scientists and mathematicians. Journal of Autism and Developmental Disorders, 31(1), 5–17.PubMedCrossRef
Beck, A. T., Steer, R. A., & Brown, G. K. (1996). Beck depression inventory-II. San Antonio, 78, 490–498.
Berthoz, S., & Hill, E. L. (2005). The validity of using self-reports to assess emotion regulation abilities in adults with autism spectrum disorder. European Psychiatry, 20(3), 291–298.PubMedCrossRef
Bird, G., & Cook, R. (2013). Mixed emotions: The contribution of alexithymia to the emotional symptoms of autism. Translational Psychiatry, 3(7), e285.PubMedPubMedCentralCrossRef
Bird, G., Silani, G., Brindley, R., White, S., Frith, U., & Singer, T. (2010). Empathic brain responses in insula are modulated by levels of alexithymia but not autism. Brain, 133(5), 1515–1525.PubMedPubMedCentralCrossRef
Cassidy, S., & Rodgers, J. (2017). Understanding and prevention of suicide in autism. The Lancet Psychiatry, 4(6), e11.CrossRefPubMed
Cassidy, S., Bradley, P., Robinson, J., Allison, C., McHugh, M., & Baron-Cohen, S. (2014). Suicidal ideation and suicide plans or attempts in adults with Asperger's syndrome attending a specialist diagnostic clinic: A clinical cohort study. The Lancet Psychiatry, 1(2), 142–147.PubMedCrossRef
Cassidy, S. A., Bradley, L., Bowen, E., Wigham, S., & Rodgers, J. (2018a). Measurement properties of tools used to assess depression in adults with and without autism spectrum conditions: A systematic review. Autism Research, 11(5), 738–754.PubMedPubMedCentralCrossRef
Cassidy, S. A., Bradley, L., Bowen, E., Wigham, S., & Rodgers, J. (2018b). Measurement properties of tools used to assess suicidality in autistic and general population adults: A systematic review. Clinical Psychology Review, 62, 56–70.PubMedCrossRef
Cole, D. A. (1988). Hopelessness, social desirability, depression, and parasuicide in two college student samples. Journal of Consulting and Clinical Psychology, 56(1), 131.PubMedCrossRef
Costa, A. P., Steffgen, G., & Samson, A. C. (2017). Expressive incoherence and alexithymia in autism spectrum disorder. Journal of Autism and Developmental Disorders, 47(6), 1659–1672.PubMedCrossRef
Cotton, C. R., Peters, D. K., & Range, L. M. (1995). Psychometric properties of the suicidal behaviors questionnaire. Death Studies, 19(4), 391–397.PubMedCrossRef
De-la-Iglesia, M., & Olivar, J. S. (2015). Risk factors for depression in children and adolescents with high functioning autism spectrum disorders. The Scientific World Journal, 2015, 127853.PubMedPubMedCentralCrossRef
Ghaziuddin, M., Ghaziuddin, N., & Greden, J. (2002). Depression in persons with autism: Implications for research and clinical care. Journal of Autism and Developmental Disorders, 32(4), 299–306.PubMedCrossRef
Ghaziuddin, M., & Zafar, S. (2008). Psychiatric comorbidity of adults with autism spectrum disorders. Clinical Neuropsychiatry, 5(1), 9–12.
Hedley, D., & Uljarević, M. (2018). Systematic review of suicide in autism spectrum disorder: Current trends and implications. Current Developmental Disorders Reports, 5(1), 65–76.CrossRef
Hedley, D., Uljarević, M., Wilmot, M., Richdale, A., & Dissanayake, C. (2017). Brief report: Social support, depression and suicidal ideation in adults with autism spectrum disorder. Journal of Autism and Developmental Disorders, 47(11), 3669–3677.PubMedCrossRef
Hill, E., Berthoz, S., & Frith, U. (2004). Brief report: Cognitive processing of own emotions in individuals with autistic spectrum disorder and in their relatives. Journal of Autism and Developmental Disorders, 34(2), 229–235.PubMedCrossRef
Hintikka, J., Honkalampi, K., Koivumaa-Honkanen, H., Antikainen, R., Tanskanen, A., Haatainen, K., et al. (2004). Alexithymia and suicidal ideation: A 12-month follow-up study in a general population. Comprehensive Psychiatry, 45(5), 340–345.PubMedCrossRef
Hirvikoski, T., Mittendorfer-Rutz, E., Boman, M., Larsson, H., Lichtenstein, P., & Bölte, S. (2016). Premature mortality in autism spectrum disorder. The British Journal of Psychiatry, 208(3), 232–238.PubMedCrossRef
Hoekstra, R. A., Bartels, M., Cath, D. C., & Boomsma, D. I. (2008). Factor structure, reliability and criterion validity of the Autism-Spectrum Quotient (AQ): A study in Dutch population and patient groups. Journal of Autism and Developmental Disorders, 38(8), 1555–1566.PubMedPubMedCentralCrossRef
Hoekstra, R. A., Vinkhuyzen, A. A., Wheelwright, S., Bartels, M., Boomsma, D. I., Baron-Cohen, S., et al. (2011). The construction and validation of an abridged version of the autism-spectrum quotient (AQ-Short). Journal of Autism and Developmental Disorders, 41(5), 589–596.PubMedCrossRef
Hofvander, B., Delorme, R., Chaste, P., Nydén, A., Wentz, E., Ståhlberg, O., et al. (2009). Psychiatric and psychosocial problems in adults with normal-intelligence autism spectrum disorders. BMC Psychiatry, 9(1), 35.PubMedPubMedCentralCrossRef
Honkalampi, K., Hintikka, J., Tanskanen, A., Lehtonen, J., & Viinamäki, H. (2000). Depression is strongly associated with alexithymia in the general population. Journal of Psychosomatic Research, 48(1), 99–104.PubMedCrossRef
Honkalampi, K., Koivumaa-Honkanen, H., Lehto, S. M., Hintikka, J., Haatainen, K., Rissanen, T., et al. (2010). Is alexithymia a risk factor for major depression, personality disorder, or alcohol use disorders? A prospective population-based study. Journal of Psychosomatic Research, 68(3), 269–273.PubMedCrossRef
Hudson, C. C., Hall, L., & Harkness, K. L. (2019). Prevalence of depressive disorders in individuals with autism spectrum disorder: A meta-analysis. Journal of Abnormal Child Psychology, 47(1), 165–175.PubMedCrossRef
Husaini, B. A., & Neff, J. A. (1980). Characteristics of live events and psychiatric impairment in rural communities. Journal of Nervous and Mental Disease, 168(3), 159–166.PubMedCrossRef
Kajanoja, J., Scheinin, N. M., Karukivi, M., Karlsson, L., & Karlsson, H. (2018). Is antidepressant use associated with difficulty identifying feelings? A brief report. Experimental and Clinical Psychopharmacology, 26(1), 2–5.PubMedCrossRef
Kessler, R. C., Borges, G., & Walters, E. E. (1999). Prevalence of and risk factors for lifetime suicide attempts in the National Comorbidity Survey. Archives of General Psychiatry, 56(7), 617–626.PubMedCrossRef
Kirby, A. V., Bakian, A. V., Zhang, Y., Bilder, D. A., Keeshin, B. R., & Coon, H. (2019). A 20-year study of suicide death in a statewide autism population. Autism Research, 12(4), 658–666.PubMedPubMedCentralCrossRef
Klinkman, M. S., Coyne, J. C., Gallo, S., & Schwenk, T. L. (1997). Can case-finding instruments be used to improve physician detection of depression in primary care? Archives of Family Medicine, 6(6), 567–573.PubMedCrossRef
Kraper, C. K., Kenworthy, L., Popal, H., Martin, A., & Wallace, G. L. (2017). The gap between adaptive behavior and intelligence in autism persists into young adulthood and is linked to psychiatric co-morbidities. Journal of Autism and Developmental Disorders, 47(10), 3007–3017.PubMedCrossRef
Kroenke, K., & Spitzer, R. L. (2002). The PHQ-9: A new depression diagnostic and severity measure. Psychiatric Annals, 32, 509–515.CrossRef
Kurita, H., & Koyama, T. (2006). Autism-Spectrum Quotient Japanese version measures mental health problems other than autistic traits. Psychiatry and Clinical Neurosciences, 60(3), 373–378.PubMedCrossRef
Lainhart, J. E. (1999). Psychiatric problems in individuals with autism, their parents and siblings. International Review of Psychiatry, 11(4), 278–298.CrossRef
Lugnegård, T., Hallerbäck, M. U., & Gillberg, C. (2011). Psychiatric comorbidity in young adults with a clinical diagnosis of Asperger syndrome. Research in developmental disabilities, 32(5), 1910–1917.PubMedCrossRef
Maisel, M. E., Stephenson, K. G., South, M., Rodgers, J., Freeston, M. H., & Gaigg, S. B. (2016). Modeling the cognitive mechanisms linking autism symptoms and anxiety in adults. Journal of Abnormal Psychology, 125(5), 692.PubMedCrossRef
Mayes, S. D., Gorman, A. A., Hillwig-Garcia, J., & Syed, E. (2013). Suicide ideation and attempts in children with autism. Research in Autism Spectrum Disorders, 7(1), 109–119.CrossRef
Mikami, K., Inomata, S., Hayakawa, N., Ohnishi, Y., Enseki, Y., Ohya, A., et al. (2009). Frequency and clinical features of pervasive developmental disorder in adolescent suicide attempts. General Hospital Psychiatry, 31(2), 163–166.PubMedCrossRef
Osman, A., Bagge, C. L., Gutierrez, P. M., Konick, L. C., Kopper, B. A., & Barrios, F. X. (2001). The Suicidal Behaviors Questionnaire-Revised (SBQ-R): Validation with clinical and nonclinical samples. Assessment, 8(4), 443–454.PubMedCrossRef
Paquette-Smith, M., Weiss, J., & Lunsky, Y. (2014). History of suicide attempts in adults with Asperger syndrome. Crisis, 35(4), 273–277.PubMedCrossRef
Radloff, L. S. (1977). The CES-D scale: A self-report depression scale for research in the general population. Applied Psychological Measurement, 1(3), 385–401.CrossRef
Raja, M., Azzoni, A., & Frustaci, A. (2011). Autism spectrum disorders and suicidality. Clinical Practice and Epidemiology in Mental Health, 7, 97–105.PubMedPubMedCentralCrossRef
Salminen, J. K., Saarijärvi, S., Äärelä, E., Toikka, T., & Kauhanen, J. (1999). Prevalence of alexithymia and its association with sociodemographic variables in the general population of Finland. Journal of Psychosomatic Research, 46(1), 75–82.PubMedCrossRef
Samson, A. C., Huber, O., & Gross, J. J. (2012). Emotion regulation in Asperger's syndrome and high-functioning autism. Emotion, 12(4), 659.PubMedCrossRef
Segers, M., & Rawana, J. (2014). What do we know about suicidality in autism spectrum disorders? A systematic review. Autism Research, 7(4), 507–521.PubMedCrossRef
Sifneos, P. E. (1973). The prevalence of ‘alexithymic’characteristics in psychosomatic patients. Psychotherapy and Psychosomatics, 22(2–6), 255–262.PubMedCrossRef
Stephenson, K. G., Luke, S. G., & South, M. (2019). Separate contributions of autistic traits and anxious apprehension, but not alexithymia, to emotion processing in faces. Autism, 23(7), 1830–1842.PubMedCrossRef
Sterling, L., Dawson, G., Estes, A., & Greenson, J. (2008). Characteristics associated with presence of depressive symptoms in adults with autism spectrum disorder. Journal of Autism and Developmental Disorders, 38(6), 1011–1018.PubMedCrossRef
Stone, M., Laughren, T., Jones, M. L., Levenson, M., Holland, P. C., Hughes, A., et al. (2009). Risk of suicidality in clinical trials of antidepressants in adults: Analysis of proprietary data submitted to US Food and Drug Administration. BMJ, 339, b2880.PubMedPubMedCentralCrossRef
Storch, E. A., Sulkowski, M. L., Nadeau, J., Lewin, A. B., Arnold, E. B., Mutch, P. J., et al. (2013). The phenomenology and clinical correlates of suicidal thoughts and behaviors in youth with autism spectrum disorders. Journal of Autism and Developmental Disorders, 43(10), 2450–2459.PubMedCrossRef
Taylor, G. J., Bagby, R. M., & Parker, D. A. (1997). Disorders of affect regulation. Alexithymia in medical and psychiatric illness. New York: Cambridge University Press.CrossRef
van Steensel, F. J., Bögels, S. M., & Dirksen, C. D. (2012). Anxiety and quality of life: Clinically anxious children with and without autism spectrum disorders compared. Journal of Clinical Child & Adolescent Psychology, 41(6), 731–738.CrossRef
Wigham, S., Barton, S., Parr, J. R., & Rodgers, J. (2017). A systematic review of the rates of depression in children and adults with high-functioning autism spectrum disorder. Journal of Mental Health Research in Intellectual Disabilities, 10(4), 267–287.CrossRef
World Health Organization. (2014). Preventing suicide: A global imperative. Geneva: World Health Organization.
World Health Organization. (2018). National suicide prevention strategies: Progress, examples and indicators. Geneva: World Health Organization.
Zahid, S., & Upthegrove, R. (2017). Suicidality in autistic spectrum disorders. Crisis, 38(4), 237–246.PubMedCrossRef
Metagegevens
Titel
Suicidality in Adults with Autism Spectrum Disorder: The Role of Depressive Symptomatology, Alexithymia, and Antidepressants
Auteurs
Andreia P. Costa
Cathia Loor
Georges Steffgen
Publicatiedatum
14-03-2020
Uitgeverij
Springer US
Gepubliceerd in
Journal of Autism and Developmental Disorders / Uitgave 10/2020
Print ISSN: 0162-3257
Elektronisch ISSN: 1573-3432
DOI
https://doi.org/10.1007/s10803-020-04433-3

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