The present study examined the influence of perceptual organization on the processing of global and local information in hierarchical patterns. In two experiments, we examined whether disturbing the spatial relationships between local elements by introducing between-element distance and size heterogeneity affected global processing dominance. The effects on global processing dominance of undistorted compound stimuli with equidistant and homogeneous local elements were compared with those of compound stimuli which presented between-element distance heterogeneity (Experiment 1) or heterogeneity in size (Experiment 2). The results showed that the global advantage effect decreased similarly under conditions of between-element distance and size heterogeneity that disturbed the spatial relationships between local elements. The results provide new evidence on the role of perceptual organization in hierarchical patterns processing.