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Netherlands Heart Journal
Gepubliceerd in:

01-05-2010 | Original article

Apoptosis during CABG surgery with the use of cardiopulmonary bypass is prominent in ventricular but not in atrial myocardium

Auteurs: W. T. Ruifrok, B. D. Westenbrink, R. A. de Boer, I. J. den Hamer, M. E. Erasmus, H. E. Mungroop, A. H. Epema, A. A. Voors, D. J. van Veldhuisen, W. H. van Gilst

Gepubliceerd in: Netherlands Heart Journal | Uitgave 5/2010

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Extract

Coronary artery bypass grafting (CABG) surgery with cardiopulmonary bypass (CPB) and cardioplegic arrest is the most commonly used cardiac surgery procedure in the Western world.1 This procedure is associated with periods of oxygen deprivation and possibly a damaging effect to the Heart. Restoration of coronary blood flow after release of the aortic cross clamp leads to ischaemia-reperfusion injury. Subsequent production of reactive oxygen species results in cardiomyocyte death due to apoptosis.2-4 These changes may cause (transient) cardiac dysfunction,5,6 and therefore limiting the duration of cardioplegic arrest may reduce cell injury. …
vorige artikel Bleeding complications after pacemaker or cardioverter-defibrillator implantation in patients receiving dual antiplatelet therapy
volgende artikel Age is an independent risk factor for left atrial dysfunction: results from an observational study
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Metagegevens
Titel
Apoptosis during CABG surgery with the use of cardiopulmonary bypass is prominent in ventricular but not in atrial myocardium
Auteurs
W. T. Ruifrok
B. D. Westenbrink
R. A. de Boer
I. J. den Hamer
M. E. Erasmus
H. E. Mungroop
A. H. Epema
A. A. Voors
D. J. van Veldhuisen
W. H. van Gilst
Publicatiedatum
01-05-2010
Uitgeverij
Bohn Stafleu van Loghum
Gepubliceerd in
Netherlands Heart Journal / Uitgave 5/2010
Print ISSN: 1568-5888
Elektronisch ISSN: 1876-6250
DOI
https://doi.org/10.1007/BF03091769

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