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Netherlands Heart Journal
Gepubliceerd in:

01-05-2010 | Interuniversity Cardiology Institute of the Netherlands

Towards a noninvasive anatomical and functional diagnostic work-up of patients with suspected coronary artery disease

Auteurs: J. G. J. Groothuis, A. M. Beek, M. R. Meijerink, S. L. Brinckman, M. B. M. Hofman, A. C. van Rossum

Gepubliceerd in: Netherlands Heart Journal | Uitgave 5/2010

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Extract

Whereas the diagnostic evaluation of patients with suspected coronary artery disease (CAD) is part of the daily routine of cardiology practice, the conventional modalities for detection of CAD have major limitations. Even though its prognostic value has been validated extensively, exercise electrocardiography only has a limited diagnostic value for detection of significant CAD, with a reported sensitivity and specificity of 68 and 77%, respectively.1 Additionally, in a large proportion of patients results are inconclusive. Although single photon emission computed tomography myocardial perfusion imaging (SPECT) is more sensitive for detection of significant CAD, it only has a moderate specificity.2 Consequently, this leads to a considerable number of unnecessary referrals for invasive coronary angiography. Furthermore, a combined SPECT stress and rest protocol involves a significant radiation burden (10-20 mSv), and requires two separate scanning sessions. …
vorige artikel Aortic dissection secondary to coronary artery intervention
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Abdulla J, Abildstrom SZ, Gotzsche O, Christensen E, Kober L, Torp-Pedersen C. 64-multislice detector computed tomography coronary angiography as potential alternative to conventional coronary angiography: a systematic review and meta-analysis. Eur Heart J. 2007;28:3042-50.
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Meijboom WB, Van Mieghem CA, van Pelt N, Weustink A, Pugliese F, Mollet NR, et al. Comprehensive assessment of coronary artery stenoses: computed tomography coronary angiography versus conventional coronary angiography and correlation with fractional flow reserve in patients with stable angina. J Am Coll Cardiol. 2008;52:636-43.
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Metagegevens
Titel
Towards a noninvasive anatomical and functional diagnostic work-up of patients with suspected coronary artery disease
Auteurs
J. G. J. Groothuis
A. M. Beek
M. R. Meijerink
S. L. Brinckman
M. B. M. Hofman
A. C. van Rossum
Publicatiedatum
01-05-2010
Uitgeverij
Bohn Stafleu van Loghum
Gepubliceerd in
Netherlands Heart Journal / Uitgave 5/2010
Print ISSN: 1568-5888
Elektronisch ISSN: 1876-6250
DOI
https://doi.org/10.1007/BF03091775

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