Psychological resilience is the capacity of individuals to adapt to stress, trauma and adversity, and this process is based on the interaction of biological, psychosocial, ecological and cultural systems as well as individual characteristics. In addition, this multidimensional approach emphasizes that resilience depends not only on individual capacities but also on environmental and social supports. Therefore, the research aims to look at the mediating role of hope and loneliness between social support and psychological resilience. 309 female university students between the ages of 18–23 participated in the study. Structural Equation Modelling (SEM) was used to test the mediation dimension of the research data. According to the results, a parallel mediating role of hope and loneliness was found between social support and psychological resilience. In the model, it was observed that hope increased with the increase in social support, loneliness decreased and thus psychological resilience increased. Strengthening social support networks increases the psychological resilience of individuals by reducing loneliness while instilling hope in individuals. It is important in terms of resilience to carry out activities that increase the social support of individuals faced with problems.